Nanobiophotonics: Tailoring Nanoscale Light-Matter Interaction in Biology
Abstract and Bio: The unique properties of light as a powerful probe and its interaction with matter have had disruptive impacts on advancing biological sciences. In this scope, nanophotonic structures have been promising for miniaturizing and enhancing light-matter interaction. In particular, integration of nanophotonic and fluidic devices holds promise for high throughput lab-on-chip biological applications. A persistent challenge, however, has been dynamic and rapid tuning of photonic devices, especially using electronic techniques which are challenging to utilize in an aqueous environment. In this talk, I will discuss our approach for photonic/fluidic/electronic integration (Electro-optofluidics1) and its prospects for large scale integrated (LSI) biophotonic chips. A distinct direction of this electro-optofluidic platform is new classes of on-chip high-throughput optical trapping devices2. Using these devices, we demonstrate sorting and manipulation of individual DNA molecules, as well as precise control of the chemical environment of a sample. I will also discuss and demonstrate other tunable optofluidic functionalities that can be realized using this platform and the outlook and prospects of this research.
1. M. Soltani et. al., “Electro-optofluidics: Achieving dynamic control on chip”, Optics Express 20, 22314 (2012)
2. M. Soltani, et. al., “Nanophotonic trapping for precise manipulation of biomolecular arrays” Nature Nanotechnology, (in press)
Mohammad Soltani is a Postdoctoral Fellow of Physics and Electrical Engineering, and a Howard Hughes Medical Institute Research Associate at Cornell University. He received his PhD in ECE (Optics and Photonics) in 2009 from Georgia Institute of Technology where he performed research on ultra-high Q silicon photonic resonators and coupled resonators, photonic crystal structures, and computational electrodynamics. His research interests are in physics and engineering of light-matter interaction at nanoscales, biophotonics, novel classical/quantum imaging and sensing techniques, optical information processing and measurement, and nanofabrication.